Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207766 | 0.84 | ACACB (0.34) | — | |
| SCHEMBL15084876 | 0.78 | KIF11 (0.32) | — | |
| SCHEMBL21533958 | 0.78 | — | — | |
| SCHEMBL21690413 | 0.74 | — | — | |
| SCHEMBL21690244 | 0.74 | — | — | |
| SCHEMBL12213882 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL20034867 | 0.74 | MAPT (0.35) | MAPT | |
| SCHEMBL14558217 | 0.74 | MAPT (0.35) | MAPT | |
| SCHEMBL14298986 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL799192 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022166920-A1 | PYRROLOPYRIDAZINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-08-11 | — | — | WO | disclosed |