Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IGF2R | P11717 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LRAT | O95237 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29184490 | 1.00 | LMNA (0.42) | LMNAKDM4EALOX15HSD17B10TSHR | |
| SCHEMBL29184489 | 1.00 | LMNA (0.42) | LMNAKDM4EALOX15HSD17B10TSHR | |
| SCHEMBL4593036 | 0.86 | GAA (0.49) | MAPK1L3MBTL1LGALS8LGALS3LGALS4 | |
| SCHEMBL16250343 | 0.85 | CA1 (0.49) | LMNAKDM4EALOX15HSD17B10TSHR | |
| SCHEMBL28326643 | 0.85 | CA1 (0.49) | LMNAKDM4EALOX15HSD17B10TSHR | |
| SCHEMBL11505243 | 0.85 | CA1 (0.49) | LMNAKDM4EALOX15HSD17B10TSHR | |
| SCHEMBL11505240 | 0.85 | CA1 (0.49) | LMNAKDM4EALOX15HSD17B10TSHR | |
| SCHEMBL7743930 | 0.85 | GAA (0.51) | IGF2RL3MBTL1LGALS8LGALS3LGALS4 | |
| SCHEMBL25312309 | 0.85 | LMNA (0.45) | LMNAKDM4EALOX15HSD17B10TSHR | |
| SCHEMBL13686584 | 0.83 | IGF2R (0.50) | LMNAKDM4EALOX15HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |