Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.48 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.48 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743930 | 0.98 | GAA (0.51) | GAALGALS8LGALS3LGALS4L3MBTL1 | |
| SCHEMBL23545830 | 0.93 | GAA (0.48) | GAALGALS8LGALS3LGALS4L3MBTL1 | |
| SCHEMBL118620 | 0.93 | GAA (0.48) | GAALGALS8LGALS3LGALS4L3MBTL1 | |
| SCHEMBL10622349 | 0.88 | GAA (0.59) | GAALGALS8LGALS3LGALS4L3MBTL1 | |
| SCHEMBL9220642 | 0.88 | GAA (0.59) | GAALGALS8LGALS3LGALS4L3MBTL1 | |
| SCHEMBL19588469 | 0.88 | LGALS3 (0.66) | LGALS8LGALS3LGALS4 | |
| SCHEMBL29184489 | 0.86 | LMNA (0.42) | LGALS8LGALS3LGALS4L3MBTL1MAPK1 | |
| SCHEMBL24724844 | 0.86 | LMNA (0.42) | LGALS8LGALS3LGALS4L3MBTL1MAPK1 | |
| SCHEMBL29184490 | 0.86 | LMNA (0.42) | LGALS8LGALS3LGALS4L3MBTL1MAPK1 | |
| SCHEMBL24930483 | 0.84 | IGF2R (0.51) | GAALGALS8LGALS3LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962896-A2 | NOVEL SYNTHETIC AGONISTS OF TOLL-LIKE RECEPTORS CONTAINING CG DINUCLEOTIDE MODIFICATIONS | Idera Pharmaceuticals, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1945653-A2 | IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS COMPRISING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES | Idera Pharmaceuticals (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1942945-A2 | IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS COMPRISING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES | Idera Pharmaceuticals (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1924284-A1 | COMPOSITIONS COMPRISING IMMUNOSTIMULATORY RNA OLIGONUCLEOTIDES AND METHODS FOR PRODUCING SAID RNA OLIGONUCLEOTIDES | Hartmann, Gunther (DE) | 2008-05-28 | — | — | EP | disclosed |
| EP-1924283-A1 | COMPOSITIONS COMPRISING IMMUNOSTIMULATORY RNA OLIGONUCLEOTIDES AND METHODS FOR PRODUCING SAID RNA OLIGONUCLEOTIDES | Hartmann, Gunther (DE) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007084237-A2 | NOVEL SYNTHETIC AGONISTS OF TOLL-LIKE RECEPTORS CONTAINING CG DINUCLEOTIDE MODIFICATIONS | IDERA PHARMACEUTICALS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007055704-A2 | IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS COMPRISING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES | IDERA PHARMACEUTICALS (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007055682-A2 | IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS COMPRISING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES | IDERA PHARMACEUTICALS (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007031322-A1 | COMPOSITIONS COMPRISING IMMUNOSTIMULATORY RNA OLIGONUCLEOTIDES AND METHODS FOR PRODUCING SAID RNA OLIGONUCLEOTIDES | HARTMANN GUNTHER (DE) | 2007-03-22 | — | — | WO | disclosed |
| WO-2007031319-A1 | COMPOSITIONS COMPRISING IMMUNOSTIMULATORY RNA OLIGONUCLEOTIDES AND METHODS FOR PRODUCING SAID RNA OLIGONUCLEOTIDES | HARTMANN GUNTHER (DE) | 2007-03-22 | — | — | WO | disclosed |