Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205961 | 0.85 | KMT2A (0.64) | KMT2ANPC1RAB9AOGAMAPT | |
| SCHEMBL25719319 | 0.84 | RAB9A (0.47) | KMT2ANPC1RAB9AOPRM1OPRK1 | |
| SCHEMBL19845916 | 0.83 | UBE2T (0.53) | KMT2ANPC1RAB9AOPRM1OPRK1 | |
| SCHEMBL25703965 | 0.82 | UBE2T (0.46) | KMT2ANPC1RAB9AOPRM1OPRK1 | |
| SCHEMBL24725715 | 0.81 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25667152 | 0.80 | ALDH1A1 (0.66) | KMT2ANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL24725714 | 0.79 | KMT2A (0.51) | KMT2AALDH1A1MAPTHTR7DRD3 | |
| SCHEMBL19598470 | 0.79 | HRH3 (0.43) | KMT2ANPC1RAB9AOGAHTR1A | |
| SCHEMBL7540818 | 0.77 | SCD (0.49) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL7543520 | 0.77 | SCD (0.49) | NPC1RAB9AALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009554-A1 | METHODS TO REDUCE ADVERSE EFFECTS OF GENE OR BIOLOGICS THERAPY | AVILAR THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |