Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | GHSR | Q92847 | 3/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862042 | 0.91 | REN (0.56) | CYP3A4SLC7A5GHSRERAP2ERAP1 | |
| SCHEMBL29728766 | 0.90 | CYP3A4 (0.60) | CYP3A4SLC7A5ERAP2ERAP1LNPEP | |
| SCHEMBL27806348 | 0.90 | CYP3A4 (0.60) | CYP3A4SLC7A5ERAP2ERAP1LNPEP | |
| SCHEMBL18862044 | 0.86 | CYP3A4 (0.57) | CYP3A4SLC7A5GHSRREN | |
| SCHEMBL21828702 | 0.83 | CYP3A4 (0.57) | CYP3A4SLC7A5ERAP2ERAP1LNPEP | |
| SCHEMBL30595016 | 0.83 | CYP3A4 (0.57) | CYP3A4SLC7A5ERAP2ERAP1LNPEP | |
| SCHEMBL27624890 | 0.83 | SLC15A2 (0.61) | ERAP2ERAP1LNPEPREN | |
| SCHEMBL23484143 | 0.82 | CYP3A4 (0.56) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL29349749 | 0.82 | CYP3A4 (0.53) | CYP3A4SLC7A5ERAP2ERAP1LNPEP | |
| SCHEMBL18862458 | 0.82 | GHSR (0.70) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |