Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 3/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 4/20 | 0.40 |
| ▸ | FNTB | P49356 | 4/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725397 | 0.92 | BACE1 (0.52) | BACE1NTSR2NTSR1CCNA2CDK2 | |
| SCHEMBL24725395 | 0.88 | BACE1 (0.48) | BACE1NTSR2NTSR1CCNA2CDK2 | |
| SCHEMBL25083892 | 0.87 | BACE1 (0.49) | BACE1NTSR2NTSR1CCNA2CDK2 | |
| SCHEMBL31663474 | 0.87 | BACE1 (0.51) | BACE1NTSR2NTSR1TLR2CCNA2 | |
| SCHEMBL29646562 | 0.86 | BACE1 (0.58) | BACE1CCNA2CDK2CCNA1GRIN2D | |
| SCHEMBL30996905 | 0.85 | BACE1 (0.54) | BACE1NTSR2NTSR1TLR2CCNA2 | |
| SCHEMBL30736017 | 0.85 | BACE1 (0.46) | BACE1NTSR2NTSR1FNTAFNTB | |
| SCHEMBL24724812 | 0.85 | BACE1 (0.47) | BACE1NTSR2NTSR1FOLH1GRIN2D | |
| SCHEMBL29696106 | 0.85 | BACE1 (0.58) | BACE1NTSR2NTSR1TLR2CCNA2 | |
| SCHEMBL24724813 | 0.85 | FOLH1 (0.46) | BACE1NTSR2NTSR1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |