Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725395 | 0.92 | BACE1 (0.48) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24725397 | 0.92 | BACE1 (0.52) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24725396 | 0.87 | BACE1 (0.47) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29465440 | 0.86 | GRIN2D (0.55) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29646562 | 0.86 | BACE1 (0.58) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29679591 | 0.86 | NTSR2 (0.52) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24724812 | 0.86 | BACE1 (0.47) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31663474 | 0.86 | BACE1 (0.51) | BACE1NTSR2NTSR1CCNA2CDK2 | |
| SCHEMBL29556987 | 0.85 | NTSR2 (0.51) | BACE1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30996905 | 0.84 | BACE1 (0.54) | BACE1NTSR2NTSR1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028338-A2 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |