Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.56 |
| ▸ | MMP8 | P22894 | 3/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 7/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | TACR3 | P29371 | 1/20 | 0.55 |
| ▸ | NMBR | P28336 | 4/20 | 0.54 |
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051310 | 0.87 | ACE (0.68) | ECE1 | |
| SCHEMBL3855087 | 0.84 | ACE (0.56) | MMP8MMP9MMP1ECE1 | |
| SCHEMBL3855086 | 0.84 | ACE (0.56) | MMP8MMP9MMP1ECE1 | |
| SCHEMBL29794215 | 0.82 | EDNRA (0.60) | MMP2MMP8MMP9MMP1MMP7 | |
| SCHEMBL23417743 | 0.81 | OPRM1 (0.55) | MMP8MMP9MMP1TACR3NMBR | |
| SCHEMBL30051401 | 0.81 | ACE (0.59) | MMP8MMP9MMP1ECE1 | |
| SCHEMBL30051825 | 0.81 | ACE (0.64) | ECE1 | |
| SCHEMBL30426315 | 0.80 | ERAP2 (0.53) | MMP2MMP8MMP9MMP1ECE1 | |
| SCHEMBL9114908 | 0.80 | MAGI3 (0.69) | MMP8MMP9MMP1ECE1 | |
| SCHEMBL9141715 | 0.80 | MAGI3 (0.69) | MMP8MMP9MMP1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |