SCHEMBL30426315

SCHEMBL30426315

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)CNC(=O)CN)C(C)C)C(=O)NCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ERAP2 Q6P179 3/20 0.53
▸ ECE1 P42892 3/20 0.53
▸ MMP1 P03956 6/20 0.53
▸ MMP2 P08253 6/20 0.52
▸ MMP8 P22894 4/20 0.52
▸ MMP9 P14780 3/20 0.52
▸ KISS1R Q969F8 2/20 0.52
▸ GRPR P30550 1/20 0.51
▸ IL1RN P18510 2/20 0.50
▸ ERAP1 Q9NZ08 1/20 0.50
▸ EDNRA P25101 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31296564 0.89 EDNRA (0.60) ERAP2ECE1MMP1MMP2MMP8
SCHEMBL31442415 0.85 KISS1R (0.58) ERAP2ECE1MMP1MMP2MMP8
SCHEMBL30120684 0.85 GHSR (0.59) ERAP2KISS1RIL1RNERAP1
SCHEMBL29658156 0.85 OPRD1 (0.57) KISS1R
SCHEMBL29380319 0.84 ERAP2 (0.64) ERAP2ECE1MMP1MMP2MMP8
SCHEMBL31536185 0.84 PRMT1 (0.55) ERAP2ECE1KISS1RGRPRIL1RN
SCHEMBL30538857 0.83 ECE1 (0.57) ERAP2ECE1MMP1MMP2MMP8
SCHEMBL30199174 0.83 NPBWR1 (0.57) ERAP2KISS1R
SCHEMBL23417743 0.82 OPRM1 (0.55) ECE1MMP1MMP8MMP9
SCHEMBL31442375 0.82 KISS1R (0.60) ERAP2MMP1MMP2MMP8MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618828-B2 Probe and method for detecting membrane-associated molecules in living cells Lazar, Josef (CZ) 2026-05-05 — — US disclosed
US-20230194503-A1 Probe and Method for Detecting Membrane-Associated Molecules in Living Cells USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2023-06-22 — — US disclosed
EP-4184168-A1 PROBE AND METHOD FOR DETECTING MEMBRANE-ASSOCIATED MOLECULES IN LIVING CELLS Ustav organicke chemie a biochemie AV CR, v.v.i. (CZ) 2023-05-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12618828-B2 Probe and method for detecting membrane-associated molecules in living cells CD2BP2, APMAP, MBOAT1 ERAP2 1236/4885ECE1 3907/4885MMP1 4624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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