Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | CTSC | P53634 | 2/20 | 0.60 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25080947 | 0.93 | KDM4E (0.61) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL27163831 | 0.93 | KDM4E (0.61) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL30812923 | 0.93 | KDM4E (0.61) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL20281025 | 0.91 | MMP2 (0.60) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL17941647 | 0.91 | MMP2 (0.60) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL10548878 | 0.91 | MMP2 (0.60) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL20657708 | 0.91 | MMP2 (0.60) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL6573635 | 0.91 | MMP2 (0.60) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL20657707 | 0.91 | MMP2 (0.60) | KDM4EMEN1MAPTTSHRKMT2A | |
| SCHEMBL8424403 | 0.90 | KDM4E (0.67) | KDM4EMEN1MAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |