Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725922 | 0.91 | ALDH1A1 (0.57) | ALDH1A1HPGDTSHRPDE4APDE4B | |
| SCHEMBL20475293 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HPGDTSHRPDE4APDE4B | |
| SCHEMBL24725913 | 0.87 | HPGD (0.58) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL24725921 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDTSHRPDE4APDE4B | |
| SCHEMBL9845474 | 0.86 | HPGD (0.74) | ALDH1A1HPGDTSHRPDE4APDE4B | |
| SCHEMBL20475314 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HPGDTSHRPDE4APDE4B | |
| SCHEMBL20475359 | 0.81 | HPGD (0.43) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL24725853 | 0.81 | GRIN1 (0.45) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL29833285 | 0.78 | HPGD (0.40) | ALDH1A1HPGDTSHRPDE4APDE4B | |
| SCHEMBL28655572 | 0.78 | HPGD (0.40) | ALDH1A1HPGDTSHRPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518754-B2 | Radiolabeled pharmaceuticals and methods of making and using same | YALE UNIVERSITY (US) | 2022-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518754-B2 | Radiolabeled pharmaceuticals and methods of making and using same | SLC18A2, SLC18A3, SLC1A2 | ALDH1A1 2700/4885HPGD 4122/4885TSHR 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.