SCHEMBL24726417

SCHEMBL24726417

NC(CCS)c1cc(F)cc(Cc2cccc(F)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.39
IDO1 P14902 3/20 0.38
AGXT P21549 2/20 0.38
SLC1A1 P43005 2/20 0.37
TDO2 P48775 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
DAO P14920 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24726665 0.77 SLC1A1 (0.44) TAAR1IDO1AGXTSLC1A1DAO
SCHEMBL3300303 0.72 TAAR1 (0.60) TAAR1IDO1AGXTDAO
SCHEMBL12706104 0.68 SLC1A1 (0.51) TAAR1IDO1AGXTSLC1A1TDO2
SCHEMBL11084543 0.68 TAAR1 (0.47) TAAR1IDO1TDO2
SCHEMBL27387510 0.67 IDO1 (0.40) IDO1TDO2
SCHEMBL24726546 0.67 GBA1 (0.42)
SCHEMBL3298408 0.66 CALM1 (0.57) TAAR1IDO1AGXTDAO
SCHEMBL23011377 0.66 MAOB (0.47) TAAR1IDO1AGXTDAO
SCHEMBL24726817 0.66 CTSA (0.45)
SCHEMBL20445783 0.65 HDAC4 (0.42) IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022234965-A1 HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 주식회사 보로노이 2022-11-10 WO disclosed