SCHEMBL24726546

SCHEMBL24726546

CN(C)c1cccc(-c2cc(F)cc(C(N)CCS)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 4/20 0.42
FYN P06241 11/20 0.37
FFAR1 O14842 1/20 0.35
GRIN1 Q05586 1/20 0.33
GRIN2B Q13224 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24726641 0.78 NOTUM (0.38) GBA1FYNFFAR1GRIN1GRIN2B
SCHEMBL24726817 0.74 CTSA (0.45) ALDH1A1
SCHEMBL24726816 0.68 FNTA (0.47) ALDH1A1
SCHEMBL30602821 0.67 ALDH1A1 (0.58) FYNFFAR1ALDH1A1
SCHEMBL24726417 0.67 TAAR1 (0.39)
SCHEMBL26378150 0.65 RXRA (0.49) FYNFFAR1ALDH1A1
SCHEMBL19698858 0.64 ALDH1A1 (0.54) FYNFFAR1ALDH1A1
SCHEMBL24527558 0.64 GBA1 (0.48) GBA1FYNSLC6A2SLC6A4ALDH1A1
SCHEMBL10620443 0.63 NPC1 (0.41) SLC6A2SLC6A4ALDH1A1MAPK1
SCHEMBL27387510 0.63 IDO1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022234965-A1 HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 주식회사 보로노이 2022-11-10 WO disclosed