Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2104955 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4ERECQLSMN1; SMN2HRH3 | |
| SCHEMBL22456382 | 0.81 | HRH3 (0.49) | HRH3TP53CHRM2CHRM1 | |
| SCHEMBL6320475 | 0.80 | LMNA (0.48) | ALDH1A1KDM4ESMN1; SMN2TP53MAPK1 | |
| SCHEMBL22456342 | 0.80 | HRH3 (0.41) | HRH3TP53 | |
| SCHEMBL14453902 | 0.80 | HRH3 (0.41) | HRH3TP53 | |
| SCHEMBL13713287 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ERECQLSMN1; SMN2HRH3 | |
| SCHEMBL14097292 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4ERECQLSMN1; SMN2HRH3 | |
| SCHEMBL23384260 | 0.78 | HRH3 (0.40) | HRH3TP53 | |
| SCHEMBL24726517 | 0.78 | HRH3 (0.40) | HRH3 | |
| SCHEMBL19288712 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4ERECQLSMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234965-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2022-11-10 | — | — | WO | disclosed |