Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200042 | 0.84 | KEAP1 (0.53) | BCHEACHEHTTSMN1; SMN2LMNA | |
| SCHEMBL13900992 | 0.82 | EGFR (0.53) | MAOBMRGPRX4 | |
| SCHEMBL24726471 | 0.80 | MAOB (0.69) | MAOBMRGPRX4FFAR1 | |
| SCHEMBL12301124 | 0.79 | MRGPRX4 (0.58) | MAOBMRGPRX4SMN1; SMN2HTR6IDO1 | |
| SCHEMBL17489331 | 0.79 | EGFR (0.47) | MAOBMRGPRX4IDO1AGXTLMNA | |
| SCHEMBL18253179 | 0.78 | MAOB (0.66) | MAOBMRGPRX4 | |
| SCHEMBL9946055 | 0.77 | MRGPRX4 (0.59) | MAOBMRGPRX4IDO1FFAR4 | |
| SCHEMBL20004351 | 0.75 | IDO1 (0.50) | MAOBMRGPRX4IDO1AGXT | |
| SCHEMBL24726478 | 0.74 | MAOB (0.57) | MAOBMRGPRX4 | |
| SCHEMBL9946034 | 0.74 | FFAR4 (0.55) | MAOBMRGPRX4HTR6IDO1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234965-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2022-11-10 | — | — | WO | disclosed |