Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.72 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.72 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.72 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.72 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.72 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.72 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.72 |
| ▸ | LTA4H | P09960 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233252 | 0.98 | MAPK1 (0.77) | MAPK1HDAC6HDAC1HDAC10HDAC8 | |
| SCHEMBL13477811 | 0.87 | HDAC6 (0.75) | MAPK1HDAC6HDAC1HDAC10HDAC8 | |
| SCHEMBL428355 | 0.85 | MAPK1 (1.00) | MAPK1HDAC6HDAC1HDAC10HDAC8 | |
| SCHEMBL13039726 | 0.85 | HDAC6 (0.97) | HDAC6HDAC1HDAC10HDAC8HDAC2 | |
| SCHEMBL19133502 | 0.84 | HDAC1 (0.71) | MAPK1HDAC6HDAC1HDAC10HDAC8 | |
| SCHEMBL16128934 | 0.84 | HDAC1 (0.73) | HDAC6HDAC1HDAC10HDAC8HDAC2 | |
| SCHEMBL13577993 | 0.84 | HDAC1 (0.73) | HDAC6HDAC1HDAC10HDAC8HDAC2 | |
| SCHEMBL1231649 | 0.84 | HDAC6 (0.71) | MAPK1HDAC6HDAC1HDAC10HDAC8 | |
| SCHEMBL14861225 | 0.84 | HDAC6 (1.00) | HDAC6HDAC1HDAC10HDAC8HDAC2 | |
| SCHEMBL1232527 | 0.84 | HDAC6 (1.00) | HDAC6HDAC1HDAC10HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159852-A1 | METHODS AND COMPOSITIONS FOR TREATING ADENOID CYSTIC CARCINOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-07-28 | — | — | WO | disclosed |
| EP-1824965-B1 | Hepatic differentiation of stem cells | UNIV BRUXELLES (BE) | 2011-10-05 | — | — | EP | disclosed |
| US-20090130064-A1 | DIFFERENTIATION OF STEM CELLS AND STABILIZATION OF PHENOTYPICAL PROPERTIES OF PRIMARY CELLS | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2009-05-21 | — | — | US | disclosed |