Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.97 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.97 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.97 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.97 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.97 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.97 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.97 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.97 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.97 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.97 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.97 |
| ▸ | LTA4H | P09960 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14861225 | 0.99 | HDAC6 (1.00) | HDAC6HDAC1HDAC2HDAC10HDAC3 | |
| SCHEMBL675763 | 0.99 | HDAC6 (1.00) | HDAC6HDAC1HDAC2HDAC10HDAC3 | |
| SCHEMBL1232527 | 0.99 | HDAC6 (1.00) | HDAC6HDAC1HDAC2HDAC10HDAC3 | |
| SCHEMBL12672623 | 0.96 | HDAC6 (0.89) | HDAC6HDAC1HDAC2HDAC10HDAC3 | |
| SCHEMBL17457489 | 0.91 | HDAC6 (0.86) | HDAC6HDAC1HDAC2HDAC10HDAC3 | |
| SCHEMBL16112746 | 0.91 | HDAC6 (0.86) | HDAC6HDAC1HDAC2HDAC10HDAC3 | |
| SCHEMBL14883307 | 0.87 | HDAC6 (0.80) | HDAC6HDAC1HDAC2HDAC10HDAC3 | |
| SCHEMBL2472647 | 0.85 | MAPK1 (0.73) | HDAC6HDAC1HDAC2HDAC10HDAC3 | |
| SCHEMBL366802 | 0.85 | HDAC6 (0.76) | HDAC6HDAC1HDAC2HDAC10HDAC3 | |
| SCHEMBL13786320 | 0.85 | HDAC6 (0.76) | HDAC6HDAC1HDAC2HDAC10HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210030899-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | THE GENERAL HOSPITAL CORPORATION | 2021-02-04 | — | — | US | disclosed |
| US-10842891-B2 | Imaging histone deacetylases with a radiotracer using positron emission tomography | THE GENERAL HOSPITAL CORPORATION (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190240357-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | THE GENERAL HOSPITAL CORPORATION | 2019-08-08 | — | — | US | disclosed |
| US-10188756-B2 | Imaging histone deacetylases with a radiotracer using positron emission tomography | THE GENERAL HOSPITAL CORPORATION (US) | 2019-01-29 | — | — | US | disclosed |
| US-20160271276-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | THE GENERAL HOSPITAL CORPORATION | 2016-09-22 | — | — | US | disclosed |
| US-20160271276-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | THE GENERAL HOSPITAL CORPORATION | 2016-09-22 | — | — | US | disclosed |
| US-20100278782-A1 | DIFFERENTIATION OF RAT LIVER EPITHELIAL CELLS INTO HEPATOCYTE-LIKE CELLS | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190240357-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | HDAC1, HDAC11, HDAC3 | HDAC6 13/4885HDAC1 1/4885HDAC2 4/4885 |
| US-10188756-B2 | Imaging histone deacetylases with a radiotracer using positron emission tomography | HDAC1, HDAC11, HDAC3 | HDAC6 13/4885HDAC1 1/4885HDAC2 4/4885 |
| US-20210030899-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | HDAC1, HDAC11, HDAC3 | HDAC6 13/4885HDAC1 1/4885HDAC2 4/4885 |
| US-20160271276-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | HDAC1, HDAC11, HDAC3 | HDAC6 13/4885HDAC1 1/4885HDAC2 4/4885 |
| US-20100278782-A1 | DIFFERENTIATION OF RAT LIVER EPITHELIAL CELLS INTO HEPATOCYTE-LIKE CELLS | MYADM, GLS2, HNF4A | HDAC6 4344/4885HDAC1 4216/4885HDAC2 3717/4885 |
| US-10842891-B2 | Imaging histone deacetylases with a radiotracer using positron emission tomography | HDAC1, HDAC11, HDAC3 | HDAC6 13/4885HDAC1 1/4885HDAC2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.