Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20669579 | 0.85 | PANK3 (0.39) | ALDH1A1MAPTFFAR4PANK3NPY5R | |
| SCHEMBL17470867 | 0.82 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTPANK3LMNA | |
| SCHEMBL13843685 | 0.82 | FFAR4 (0.36) | KDM4EALDH1A1MAPTFFAR4PANK3 | |
| SCHEMBL24726638 | 0.80 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPTFFAR4PANK3 | |
| SCHEMBL12728816 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1MAPTFFAR4SOS1 | |
| SCHEMBL24726654 | 0.78 | LGMN (0.37) | KDM4EALDH1A1MAPTFFAR4PANK3 | |
| SCHEMBL10022373 | 0.76 | NOTUM (0.51) | KDM4EALDH1A1FAAHPANK3 | |
| SCHEMBL10022346 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1MAPTPANK3KDM5B | |
| SCHEMBL21267576 | 0.72 | KDM4E (0.43) | KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL18794507 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTFFAR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234965-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2022-11-10 | — | — | WO | disclosed |