Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 7/20 | 0.63 |
| ▸ | HTR2A | P28223 | 7/20 | 0.63 |
| ▸ | HTR1B | P28222 | 6/20 | 0.63 |
| ▸ | HTR1A | P08908 | 5/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.63 |
| ▸ | HTR2C | P28335 | 5/20 | 0.63 |
| ▸ | HTR1E | P28566 | 5/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.63 |
| ▸ | HTR7 | P34969 | 5/20 | 0.63 |
| ▸ | HRH1 | P35367 | 5/20 | 0.63 |
| ▸ | DRD3 | P35462 | 5/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.63 |
| ▸ | HTR2B | P41595 | 5/20 | 0.63 |
| ▸ | HTR5A | P47898 | 5/20 | 0.63 |
| ▸ | HTR6 | P50406 | 5/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.63 |
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18383116 | 0.80 | HTR1D (0.69) | HTR1DHTR2AHTR1BHTR1AADRA2A | |
| SCHEMBL3773674 | 0.80 | GPR84 (0.67) | HTR1DHTR2AHTR1BHTR1AADRA2A | |
| SCHEMBL7651463 | 0.79 | HTR1D (0.67) | HTR1DHTR2AHTR1BHTR1AADRA2A | |
| SCHEMBL22462305 | 0.78 | HTR1D (1.00) | HTR1DHTR2AHTR1BHTR1AADRA2A | |
| SCHEMBL27504320 | 0.78 | HTR1D (0.71) | HTR1DHTR2AHTR1BHTR1AADRA2A | |
| SCHEMBL1722931 | 0.77 | HTR1D (0.65) | HTR1DHTR2AHTR1BHTR1AADRA2A | |
| SCHEMBL31567644 | 0.77 | HTR1D (0.65) | HTR1DHTR2AHTR1BHTR1AADRA2A | |
| SCHEMBL24692975 | 0.77 | HTR2A (0.79) | HTR1DHTR2AHTR1BHTR1AADRA2A | |
| SCHEMBL3052894 | 0.76 | HTR2A (0.55) | HTR1DHTR2AHTR1BHTR1AADRA2A | |
| SCHEMBL3047574 | 0.76 | HTR2A (0.55) | HTR1DHTR2AHTR1BHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022211518-A1 | NOVEL COMPOUND AND USE THEREOF IN TREATING PSORIASIS, ASTHMA, OR SYSTEMIC LUPUS ERYTHEMATOSUS | 파렌키마바이오텍 주식회사 | 2022-10-06 | — | — | WO | disclosed |