Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338046 | 0.75 | — | — | |
| SCHEMBL11663035 | 0.70 | — | — | |
| SCHEMBL11204922 | 0.67 | ALOX15 (0.34) | GRIK1GRIK2ALDH1A1 | |
| SCHEMBL18638830 | 0.65 | — | — | |
| SCHEMBL15779620 | 0.65 | GRIK1 (0.37) | GRIK1GRIK2ALDH1A1 | |
| SCHEMBL28502719 | 0.65 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL38654385 | 0.65 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL109608 | 0.62 | — | — | |
| SCHEMBL8388179 | 0.62 | ALOX15 (0.44) | GRIK1GRIK2ALDH1A1 | |
| SCHEMBL8814322 | 0.62 | ALDH1A1 (0.34) | GRIK1GRIK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159454-A1 | BET SUBFAMILY INHIBITORS AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2022-07-28 | — | — | WO | disclosed |