SCHEMBL24728166

SCHEMBL24728166

CC1(C)C=Cc2c(ccc3cc(C(=O)/C=C/c4ccccc4)oc23)O1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.52
ACHE P22303 2/20 0.52
ODC1 P11926 2/20 0.52
BCHE P06276 1/20 0.52
BACE1 P56817 1/20 0.52
HIF1AN Q9NWT6 1/20 0.48
MAPT P10636 3/20 0.44
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
ALDH1A1 P00352 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
LMNA P02545 2/20 0.44
NFKB1 P19838 2/20 0.44
USP2 O75604 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728324 0.88 ACHE (0.66) PTPN1ACHEODC1BCHEBACE1
SCHEMBL24728311 0.87 MAOB (0.53) ACHEODC1BCHEHIF1AN
SCHEMBL29822997 0.85 ACHE (0.55) PTPN1ACHEODC1BCHEBACE1
SCHEMBL24728239 0.85 ACHE (0.55) PTPN1ACHEODC1BCHEBACE1
SCHEMBL24728230 0.84 MAPT (0.45) PTPN1ACHEODC1BCHEBACE1
SCHEMBL29822893 0.84 ODC1 (0.57) ACHEODC1HIF1ANMEN1KMT2A
SCHEMBL24728218 0.84 ODC1 (0.57) ACHEODC1HIF1ANMEN1KMT2A
SCHEMBL24728235 0.84 PTPN1 (0.40) PTPN1ACHEODC1BCHEBACE1
SCHEMBL24728221 0.84 HIF1AN (0.50) ACHEODC1BCHEHIF1ANMAPT
SCHEMBL29823031 0.84 HIF1AN (0.50) ACHEODC1BCHEHIF1ANMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022158624-A1 NOVEL BENZOPYRAN DERIVATIVE COMPOUND, PREPARATION METHOD THEREFOR, AND ANTICANCER COMPOSITION COMPRISING SAME 연세대학교 산학협력단 2022-07-28 WO disclosed