Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25140466 | 0.85 | MEN1 (0.52) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL6284235 | 0.82 | KDM4E (0.44) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL19606563 | 0.81 | CASP2 (0.61) | MEN1KMT2ACASP2NAAAEPHX1 | |
| SCHEMBL23568447 | 0.81 | PAOX (0.47) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL6284516 | 0.80 | KDM4E (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2CASP2 | |
| SCHEMBL19401722 | 0.80 | MEN1 (0.46) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL13311543 | 0.79 | CA1 (0.46) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL21613628 | 0.79 | CASP2 (0.64) | MEN1KMT2ACASP2NAAAEPHX1 | |
| SCHEMBL21765847 | 0.79 | KDM4E (0.67) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL22340820 | 0.79 | CASP2 (0.64) | MEN1KMT2ACASP2NAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116911-A1 | ANTI-FRα ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 百奥泰生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023061457-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 百奥泰生物制药股份有限公司 | 2023-04-20 | — | — | WO | disclosed |
| WO-2022253284-A1 | DRUG CONJUGATE AND USE THEREOF | 百奥泰生物制药股份有限公司 | 2022-12-08 | — | — | WO | disclosed |