SCHEMBL24728359

SCHEMBL24728359

CC1CC2CC(C)C3(c4ccccc4-c4cccc(Nc5cccc(-c6ccccc6)c5)c43)C(C1)C2

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
SYK P43405 3/20 0.32
AKR1C3 P42330 1/20 0.32
STK10 O94804 1/20 0.30
SLK Q9H2G2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728650 0.92 CTSD (0.32)
SCHEMBL24728358 0.87 SIRT2 (0.40) SIRT2SIRT1SYKAKR1C3STK10
SCHEMBL24728440 0.87 PDK2 (0.37) SYKSTK10SLK
SCHEMBL22797600 0.86 SIRT2 (0.39) SIRT2SIRT1SYKAKR1C3STK10
SCHEMBL25457878 0.83 PDK2 (0.32)
SCHEMBL22799278 0.82 MEN1 (0.35) SIRT2SIRT1AKR1C3
SCHEMBL22797649 0.78 MEN1 (0.34) AKR1C3STK10SLK
SCHEMBL23571922 0.78 MEN1 (0.38)
SCHEMBL22799310 0.78 SIRT2 (0.39) SIRT2SIRT1SYKAKR1C3STK10
SCHEMBL23628260 0.77 MAPK14 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220388944-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388944-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 SIRT2 3932/4885SIRT1 3690/4885SYK 3316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.