SCHEMBL24728495

SCHEMBL24728495

CC1(C)CNC(C)(C)c2cccc3cccc1c23

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 1/20 0.37
ALDH1A1 P00352 5/20 0.32
KDM4E B2RXH2 4/20 0.32
MAPT P10636 4/20 0.32
HPGD P15428 4/20 0.32
HSD17B10 Q99714 4/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
GAA P10253 2/20 0.32
APP P05067 2/20 0.32
SNCA P37840 2/20 0.32
APAF1 O14727 2/20 0.32
NSD2 O96028 1/20 0.32
TYMS P04818 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 2/20 0.31
TSHR P16473 2/20 0.31
CYP1A1 P04798 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26007418 0.77 KDM4E (0.38) RAD52ALDH1A1KDM4EMAPTHPGD
SCHEMBL5594716 0.76 RAD52 (0.45) RAD52ALDH1A1KDM4EMAPTHPGD
SCHEMBL21663222 0.74 RAD52 (0.46) RAD52ALDH1A1KDM4EMAPTHPGD
SCHEMBL21663225 0.74 PARP1 (0.40) RAD52ALDH1A1KDM4EMAPTHPGD
SCHEMBL14262737 0.65 RAD52 (0.41) RAD52ALDH1A1KDM4EMAPTHPGD
SCHEMBL14392561 0.64 ALDH1A1 (0.41) RAD52ALDH1A1KDM4EMAPTHPGD
SCHEMBL21662926 0.64 RAD52 (0.34) RAD52ALDH1A1KDM4EMAPTHPGD
SCHEMBL12878884 0.64 CYP3A4 (0.33) ALDH1A1KDM4EMAPTHPGDHSD17B10
Methyl Alcohol SCHEMBL14815617 0.64 CYP3A4 (0.39) RAD52ALDH1A1KDM4EMAPTHPGD
Ammonia Solution, Strong SCHEMBL10616781 0.63 KDM1A (0.38) RAD52ALDH1A1KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220388944-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388944-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 RAD52 3741/4885ALDH1A1 1303/4885KDM4E 2351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.