SCHEMBL24728630

SCHEMBL24728630

Cn1c2ccc(-c3ccccc3)cc2c2ccc3oc4ccc(-c5ccccc5)cc4c3c21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 1/20 0.43
MAOB P27338 1/20 0.43
PLA2G2A P14555 3/20 0.39
PLA2G4A P47712 3/20 0.39
PRKDC P78527 3/20 0.37
GAA P10253 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
NR4A2 P43354 2/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
PLA2G10 O15496 1/20 0.35
PGR P06401 1/20 0.34
GRM2 Q14416 1/20 0.34
BRD4 O60885 1/20 0.34
TSPO P30536 1/20 0.34
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728708 0.95 PLA2G2A (0.43) LIMK1MAOBPLA2G2APLA2G4APRKDC
SCHEMBL25681591 0.93 RXRA (0.43) LIMK1MAOBPLA2G2APLA2G4APRKDC
SCHEMBL25681589 0.85 RXRA (0.43) LIMK1MAOBPLA2G2APLA2G4APRKDC
SCHEMBL25681542 0.85 LIMK1 (0.48) LIMK1MAOBPLA2G2APLA2G4AGAA
SCHEMBL25678820 0.83 PLA2G2A (0.41) LIMK1MAOBPLA2G2APLA2G4APRKDC
SCHEMBL18565472 0.78 AHR (0.39) MAOBPRKDCGAAL3MBTL1KDM4E
SCHEMBL23348107 0.78 MAOB (0.44) LIMK1MAOBGAAKDM4EMAPT
SCHEMBL25612911 0.78 PLA2G2A (0.45) LIMK1PLA2G2APLA2G4APRKDCGAA
SCHEMBL24728559 0.78 KDM4E (0.45) MAOBGAAKDM4EMEN1MAPT
SCHEMBL9889863 0.77 PLA2G2A (0.55) PLA2G2APLA2G4APRKDCGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4102588-A1 HOST MATERIAL, COMPOSITION, AND ORGANIC ELECTROLUMINESCENT ELEMENT Kyulux, Inc. (JP) 2022-12-14 EP disclosed