SCHEMBL24728796

SCHEMBL24728796

CCCCC/C=C\CCN(CCO)CCCCCCCCCOC(=O)CCCCCCCCCN(CCC)CCCCCCCCCC(=O)OCCCCCCCCCCN(CC/C=C\CCCCC)CCN=O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.47
EPHX2 P34913 1/20 0.44
FAAH O00519 1/20 0.44
DGKA P23743 2/20 0.43
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
PRKCE Q02156 1/20 0.42
PRKCQ Q04759 1/20 0.42
PRKCD Q05655 1/20 0.42
PRKCA P17252 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
DNM1 Q05193 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728798 0.88 MGLL (0.54) MGLLEPHX2FAAHDGKAPRKCE
SCHEMBL24728761 0.88 MGLL (0.59) MGLLEPHX2FAAHDGKAPRKCE
SCHEMBL24728640 0.88 EPHX2 (0.44) MGLLEPHX2FAAHDGKAPRSS1
SCHEMBL24728757 0.87 MGLL (0.53) MGLLEPHX2FAAHDGKAPRKCE
SCHEMBL24728679 0.87 PRSS1 (0.53) EPHX2FAAHDGKAPRSS1PRSS2
SCHEMBL24728713 0.87 MGLL (0.48) MGLLEPHX2FAAHDGKAPRSS1
SCHEMBL24729084 0.85 EPHX2 (0.51) MGLLEPHX2FAAHDGKAPRKCE
SCHEMBL24728619 0.85 MGLL (0.66) MGLLEPHX2FAAHDGKAALDH1A1
SCHEMBL24728610 0.85 MGLL (0.66) MGLLEPHX2FAAHDGKAALDH1A1
SCHEMBL24485282 0.85 MGLL (0.66) MGLLEPHX2FAAHDGKAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022168085-A1 LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-08-11 WO disclosed