SCHEMBL24728980

SCHEMBL24728980

O=C(CS)NC(CO)C(=O)NC(CO)C(=O)NC(CO)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MME P08473 8/20 0.46
TGFBR1 P36897 3/20 0.46
ACE P12821 1/20 0.43
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
NFKB1 P19838 1/20 0.38
PTGS2 P35354 1/20 0.38
THPO P40225 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FNTA P49354 1/20 0.35
FNTB P49356 1/20 0.35
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35
NMT2 O60551 1/20 0.33
NMT1 P30419 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30775998 1.00 MME (0.46) MMETGFBR1ACEKDM4EMAPT
SCHEMBL26669053 1.00 MME (0.46) MMETGFBR1ACEKDM4EMAPT
SCHEMBL26964341 0.92 TGFBR1 (0.52) MMETGFBR1ACEKDM4EMAPT
SCHEMBL27125557 0.92 TGFBR1 (0.52) MMETGFBR1ACEKDM4EMAPT
SCHEMBL16781665 0.83 MME (0.36) MMETGFBR1ACEKDM4EMAPT
Serine SCHEMBL29107953 0.81 TGFBR1 (0.47) MMETGFBR1KDM4EMAPTTHRB
SCHEMBL30945534 0.81 ACE (0.45) MMETGFBR1ACEKDM4EMAPT
SCHEMBL29456599 0.81 TGFBR1 (0.50) MMETGFBR1CA2CA1NMT2
SCHEMBL4086458 0.81 TGFBR1 (0.50) MMETGFBR1CA2CA1NMT2
SCHEMBL25774671 0.81 TGFBR1 (0.40) MMETGFBR1ACEKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025125621-A1 CANCER-ASSOCIATED PROTEIN-TARGETED STRONG OR COVALENTLY BINDING PRECURSOR COMPOUNDS AND RADIOTRACERS RADIOVAXX GMBH (DE) 2025-06-19 WO claimed
WO-2025125335-A1 CYTOTOXIC OR RADIOPHARMACEUTICAL COMPOUND WITH SULFUR FLUORIDE EXCHANGE GROUP RADIOVAXX GMBH (DE) 2025-06-19 WO disclosed
WO-2025125621-A1 CANCER-ASSOCIATED PROTEIN-TARGETED STRONG OR COVALENTLY BINDING PRECURSOR COMPOUNDS AND RADIOTRACERS RADIOVAXX GMBH (DE) 2025-06-19 WO disclosed
WO-2023222558-A1 PRECURSOR AND THERANOSTIC RADIOTRACER WITH IMPROVED TUMOR RETENTION ZOUNEK ALEXIS NIKOLAI (DE) 2023-11-23 WO disclosed
WO-2023165987-A1 PRECURSOR MARKERS AND RADIOTRACERS WITH THREE OR MORE TARGETING VECTORS FOR THERANOSTICS USED IN NUCLEAR MEDICINE Atoms for Cure GmbH (DE) 2023-09-07 WO disclosed
WO-2022258637-A1 TRISLINKER-CONJUGATED DIMERIC LABELLING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Atoms for Cure GmbH (DE) 2022-12-15 WO disclosed