Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24729555 | 0.91 | SCD (0.72) | SCDRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL29947467 | 0.91 | SCD (0.72) | SCDRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL24729361 | 0.85 | NPC1 (0.61) | SCDRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL4921088 | 0.84 | SCD (1.00) | SCDRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL24729561 | 0.82 | HSD17B10 (0.55) | SCDRAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL24730598 | 0.82 | NPC1 (0.53) | SCDRAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL28953071 | 0.80 | RAB9A (0.62) | SCDRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL24729256 | 0.79 | HSD17B10 (0.56) | SCDRAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL10065620 | 0.79 | LRRK2 (0.76) | SCDRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL2190910 | 0.79 | SCD (0.72) | SCDRAB9ANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |