SCHEMBL24729924

SCHEMBL24729924

CCOC1CN(I)CC1NC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23938365 0.78
SCHEMBL24729921 0.73
SCHEMBL23938167 0.72 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2
SCHEMBL19290505 0.70 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2
SCHEMBL21386186 0.70
SCHEMBL25036886 0.68
SCHEMBL23938048 0.67
SCHEMBL13866430 0.65 MAPK1 (0.45) ALDH1A1SMN1; SMN2
SCHEMBL9032552 0.65 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2
SCHEMBL6888671 0.65 MAPK1 (0.45) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11524966-B1 Carboxamides as ubiquitin-specific protease inhibitors VALO HEALTH, INC. (US) 2022-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524966-B1 Carboxamides as ubiquitin-specific protease inhibitors USP28, USP25, USP24 ALDH1A1 2167/4885SMN1; SMN2 2918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.