SCHEMBL24730100

SCHEMBL24730100

B[C@H]1C[C@@H](OC(=O)C(C)(C)CC(C)(C)CN)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 14/20 0.32
P2RY4 P51582 6/20 0.32
RNASEL Q05823 2/20 0.32
POLB P06746 1/20 0.31
POLA1 P09884 1/20 0.31
POLD1 P28340 1/20 0.31
P2RX3 P56373 1/20 0.31
P2RX4 Q99571 1/20 0.31
P2RX2 Q9UBL9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24730958 0.88 P2RY2 (0.30) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL23197870 0.88 P2RY2 (0.30) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL23197957 0.86 POLB (0.36) P2RY2P2RY4RNASELPOLBPOLA1
SCHEMBL271990 0.82 P2RY2 (0.37) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL272516 0.78 P2RY2 (0.36) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL25141885 0.78 P2RY2 (0.37) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL18462970 0.77 P2RY2 (0.35) P2RY2P2RY4RNASELPOLBPOLA1
SCHEMBL271873 0.77 P2RY2 (0.35) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL22002630 0.77 P2RY2 (0.37) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL21555519 0.77 P2RY2 (0.37) P2RY2P2RY4POLBPOLA1POLD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220389049-A1 REVERSIBLE TERMINATORS FOR DNA SEQUENCING AND METHODS OF USING THE SAME CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (VG) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389049-A1 REVERSIBLE TERMINATORS FOR DNA SEQUENCING AND METHODS OF USING THE SAME RNGTT, NT5C3B, NSUN2 P2RY2 2614/4885P2RY4 1458/4885RNASEL 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.