Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726273 | 0.96 | TSHR (0.58) | TSHRNAAAIDO1AGXTLTA4H | |
| SCHEMBL6267162 | 0.96 | TSHR (0.58) | TSHRNAAAIDO1AGXTLTA4H | |
| SCHEMBL5848836 | 0.92 | TSHR (0.54) | TSHRNAAAIDO1AGXTLTA4H | |
| SCHEMBL14673871 | 0.89 | TSHR (0.56) | TSHRNAAAIDO1AGXTLTA4H | |
| SCHEMBL9671825 | 0.87 | TSHR (0.43) | TSHRNAAAIDO1AGXTLTA4H | |
| SCHEMBL1001167 | 0.86 | TSHR (0.58) | TSHRNAAAIDO1AGXTLTA4H | |
| SCHEMBL1991359 | 0.85 | TSHR (0.78) | TSHRNAAAIDO1AGXTLTA4H | |
| SCHEMBL3488296 | 0.85 | TSHR (0.56) | TSHRNAAAIDO1LTA4HTDP1 | |
| SCHEMBL8998380 | 0.85 | TSHR (0.56) | TSHRNAAAIDO1AGXTLTA4H | |
| SCHEMBL344059 | 0.84 | TSHR (0.61) | TSHRNAAAIDO1AGXTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777661-A1 | NATRIURETIC AND ANTI-HYPERTENSIVE COMPOUNDS | LOMA LINDA UNIVERSITY MEDICAL CENTER (US) | 1997-06-11 | — | — | EP | claimed |
| WO-1996002522-A1 | NATRIURETIC AND ANTI-HYPERTENSIVE COMPOUNDS | LOMA LINDA UNIVERSITY MEDICAL CENTER (US) | 1996-02-01 | — | — | WO | claimed |
| WO-2025229046-A1 | SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME | MOLIUS SAGLIK TEKNOLOJILERI ANONIM SIRKETI (TR) | 2025-11-06 | — | — | WO | disclosed |
| EP-4644375-A1 | SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME | Molius Saglik Teknolojileri Anonim Sirketi (TR) | 2025-11-05 | — | — | EP | disclosed |
| US-11833162-B2 | Macrocyclic derivatives, process for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2023-12-05 | — | — | US | disclosed |
| CN-109134802-B | Phosphorus-containing halogen-free flame-retardant thermoplastic polyurethane elastomer composition and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-3700911-B1 | NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2023-09-06 | — | — | EP | disclosed |
| CN-112334441-B | Polymerizable polar compound, liquid crystal composition, and liquid crystal display element | 捷恩智株式会社 | 2023-08-01 | — | — | CN | disclosed |
| CN-111511750-B | Macrocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2023-06-13 | — | — | CN | disclosed |
| US-11631897-B2 | Ionic liquid additive for lithium-ion battery | HIGH TECH BATTERY INC. (TW) | 2023-04-18 | — | — | US | disclosed |
| US-11626620-B2 | Ionic liquid additive for lithium-ion battery | HIGH TECH BATTERY INC. (TW) | 2023-04-11 | — | — | US | disclosed |
| US-5846967-A | Natriuretic and anti-hypertensive compounds | LOMA LINDA UNIVERSITY MEDICAL CENTER (US) | 1998-12-08 | — | — | US | disclosed |
| CN-1172108-A | Triazole derivative or salt thereof | SS PHARMACEUTICAL CO (JP) | 1998-02-04 | — | — | CN | disclosed |
| EP-0814079-A1 | Triazole derivative or salt thereof | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-12-29 | — | — | EP | disclosed |
| EP-0777661-A1 | NATRIURETIC AND ANTI-HYPERTENSIVE COMPOUNDS | LOMA LINDA UNIVERSITY MEDICAL CENTER (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996002522-A1 | NATRIURETIC AND ANTI-HYPERTENSIVE COMPOUNDS | LOMA LINDA UNIVERSITY MEDICAL CENTER (US) | 1996-02-01 | — | — | WO | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4647565-A | 2-(2-quinazolinylaminoalkoxymethyl)-1,4-dihydropyridine derivatives as cardiovascular agents | PFIZER INC. (US) | 1987-03-03 | — | — | US | disclosed |
| EP-0168151-A1 | Dihydropyridine cardiovascular agents | Pfizer Limited (GB) | 1986-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11833162-B2 | Macrocyclic derivatives, process for preparing same and pharmaceutical compositions containing same | C1R, F12, RDX | TSHR 493/4885NAAA 3561/4885IDO1 3955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.