Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001167 | 0.98 | TSHR (0.58) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL3488296 | 0.92 | TSHR (0.56) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL10826161 | 0.90 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL6941525 | 0.90 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL3289641 | 0.90 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL10825883 | 0.90 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL31018369 | 0.86 | L3MBTL1 (0.51) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL31018373 | 0.85 | L3MBTL1 (0.50) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL2473034 | 0.85 | TSHR (0.64) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL2640223 | 0.84 | TSHR (0.70) | TSHRTDP1L3MBTL1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536737-A | Compound having prolyl endopeptidase inhibitory activity and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 1996-07-16 | — | — | US | disclosed |