Barbituric Acid

Barbituric Acid

SCHEMBL247308

CCCC.O=C1CC(=O)NC(=O)N1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP1A2 P05177 1/20 0.44
HPGD P15428 1/20 0.44
HIF1A Q16665 1/20 0.44
LMNA P02545 5/20 0.40
KDM4E B2RXH2 3/20 0.37
CYP2C19 P33261 2/20 0.37
CRBN Q96SW2 3/20 0.35
TSHR P16473 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CYP3A4 P08684 2/20 0.34
GABRB3 P28472 1/20 0.34
OPRD1 P41143 1/20 0.34
GABRA2 P47869 1/20 0.34
GABRB2 P47870 1/20 0.34
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
DRD2 P14416 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Barbituric Acid SCHEMBL38707 0.85
Barbituric Acid SCHEMBL4560317 0.85 ALDH1A1 (0.55) HSD17B10ALDH1A1CYP1A2HPGDHIF1A
Barbituric Acid SCHEMBL9941322 0.85
Barbituric Acid SCHEMBL27648120 0.82 ALDH1A1 (0.54) HSD17B10ALDH1A1CYP1A2HPGDHIF1A
Barbituric Acid SCHEMBL11674448 0.82 ALDH1A1 (0.54) HSD17B10ALDH1A1CYP1A2HPGDHIF1A
Barbituric Acid SCHEMBL1972516 0.82 ALDH1A1 (0.52) HSD17B10ALDH1A1CYP1A2HPGDHIF1A
Barbituric Acid SCHEMBL11379882 0.82 ALDH1A1 (0.52) HSD17B10ALDH1A1CYP1A2HPGDHIF1A
Barbituric Acid SCHEMBL1974368 0.82 ALDH1A1 (0.52) HSD17B10ALDH1A1CYP1A2HPGDHIF1A
Barbituric Acid SCHEMBL1973830 0.82 ALDH1A1 (0.52) HSD17B10ALDH1A1CYP1A2HPGDHIF1A
Barbituric Acid SCHEMBL5924412 0.82 ALDH1A1 (0.52) HSD17B10ALDH1A1CYP1A2HPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4684196-A1 METHODS FOR ANTIGEN RETRIEVAL OF A FIXED SAMPLE FOR MULTIPLE APPLICATIONS Resolve BioSciences GmbH (DE) 2026-01-28 EP claimed
EP-3804769-B1 HYALURONIC ACID FILLER HAVING HIGH VISCOELASTICITY AND HIGH COHESIVENESS LG CHEMICAL LTD (KR) 2025-05-21 EP claimed
WO-2024193972-A1 METHODS FOR ANTIGEN RETRIEVAL OF A FIXED SAMPLE FOR MULTIPLE APPLICATIONS RESOLVE BIOSCIENCES GMBH (DE) 2024-09-26 WO claimed
EP-4431531-A1 METHOD FOR PREPARING COMPOSITION CONTAINING HYALURONIC ACID CROSSLINKED PRODUCT Yoo Young Pharm Co., Ltd. (KR) 2024-09-18 EP claimed
US-12002951-B2 Buffer interlayers in membraneless high voltage batteries URBAN ELECTRIC POWER INC. (US) 2024-06-04 US claimed
US-20240047728-A1 ELECTRODE-LESS, MEMBRANE-LESS HIGH VOLTAGE BATTERIES URBAN ELECTRIC POWER INC. 2024-02-08 US claimed
EP-3804770-B1 HYALURONIC ACID FILLER HAVING HIGH LIFT CAPACITY AND LOW INJECTION FORCE LG CHEMICAL LTD (KR) 2023-12-06 EP claimed
WO-2023085832-A1 METHOD FOR PREPARING COMPOSITION CONTAINING HYALURONIC ACID CROSSLINKED PRODUCT 주식회사 유영제약 2023-05-19 WO claimed
US-11434206-B2 Process for the preparation of diphenylpyrazine derivatives HONOUR (R&D) (IN) 2022-09-06 US claimed
WO-2022140603-A1 ELECTRODE-LESS, MEMBRANE-LESS HIGH VOLTAGE BATTERIES URBAN ELECTRIC POWER INC. (US) 2022-06-30 WO claimed
EP-2470877-A1 METHOD AND APPARATUS FOR ANTIGEN RETRIEVAL PROCESS General Electric Company (US) 2012-07-04 EP claimed
US-8067241-B2 Method and apparatus for antigen retrieval process GENERAL ELECTRIC COMPANY (US) 2011-11-29 US claimed
WO-2011025442-A1 METHOD AND APPARATUS FOR ANTIGEN RETRIEVAL PROCESS GENERAL ELECTRIC COMPANY (US) 2011-03-03 WO claimed
US-20110053171-A1 METHOD AND APPARATUS FOR ANTIGEN RETRIEVAL PROCESS GENERAL ELECTRIC COMPANY (US) 2011-03-03 US claimed
CN-101081305-B Liquid deodorant KAO CORP 2010-11-10 CN claimed
EP-1161589-B1 LIQUID DEODORANT KAO CORP (JP) 2003-07-23 EP claimed
CN-1066480-C Method for increasing injectability of reservoir polymer PETROLEUM RECOVERY EFFICIENCY (CN) 2001-05-30 CN claimed
CN-1144256-A Method for increasing injectability of reservoir polymer INST OF PETROLEUM RECOVERY EFF (CN) 1997-03-05 CN claimed
CN-1128350-A Compound salt system for determination of water-soluble superpolymer molecular weight CHEMICAL INST CHINESE ACADEMY (CN) 1996-08-07 CN claimed
US-4036823-A Barbituric acid antigenic conjugates, their preparation, antibodies and use BIOLOGICAL DEVELOPMENTS, INC. (US) 1977-07-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11434206-B2 Process for the preparation of diphenylpyrazine derivatives SELPLG, SELP, SPR HSD17B10 3023/4885ALDH1A1 2680/4885CYP1A2 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.