SCHEMBL24733095

SCHEMBL24733095

CCCCOc1nc(N)c2nc(C)n(C3CCCCO3)c2n1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29809145 0.89 TLR7 (0.48) TLR7
SCHEMBL567681 0.89 TLR7 (0.48) TLR7
SCHEMBL29809327 0.88 TLR7 (0.47) TLR7
SCHEMBL567233 0.88 TLR7 (0.47) TLR7
SCHEMBL2486847 0.87 TLR7 (0.47) TLR7
SCHEMBL24732907 0.87 TLR7 (0.49) TLR7
SCHEMBL24732698 0.87 TLR7 (0.47) TLR7
SCHEMBL24732950 0.86 TLR7 (0.46) TLR7
SCHEMBL24732700 0.84 TLR7 (0.46) TLR7
SCHEMBL567355 0.82 ADORA2A (0.55) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022161420-A1 CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翊石医药科技有限公司 2022-08-04 WO disclosed