SCHEMBL2473368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6713930	0.75	AOC3 (0.46)	ESR1ESR2AOC3CA1CA2
	SCHEMBL6712538	0.75	BRD4 (0.48)	ESR1ESR2AOC3CA1CA2
	SCHEMBL2477916	0.75	DPP4 (0.44)	ESR1ESR2AOC3CA1CA2
	SCHEMBL28430363	0.73	ESR1 (0.56)	ESR1ESR2AOC3CA1CA2
	SCHEMBL2473798	0.73	ESR1 (0.46)	ESR1ESR2AOC3CA1CA2
	SCHEMBL2478003	0.72	ESR1 (0.45)	ESR1ESR2AOC3CA1CA2
	SCHEMBL541948	0.71	ESR1 (0.55)	ESR1ESR2AOC3CA1CA2
	SCHEMBL24566859	0.71	ESR1 (0.50)	ESR1ESR2AOC3CA1CA2
	SCHEMBL2475986	0.71	ESR1 (0.39)	ESR1ESR2AOC3CA1CA2
	SCHEMBL6711107	0.70	ESR1 (0.50)	ESR1ESR2AOC3CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.