Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476211 | 0.88 | HDAC1 (0.56) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL3835935 | 0.88 | HDAC1 (0.47) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL2476443 | 0.85 | HDAC1 (0.56) | HDAC1HDAC2HDAC3NCOR2ALDH1A1 | |
| SCHEMBL2475971 | 0.82 | HDAC1 (0.54) | HDAC1HDAC2HDAC3MEN1KMT2A | |
| SCHEMBL2478981 | 0.82 | NPC1 (0.42) | HDAC1HDAC2HDAC3NCOR2MEN1 | |
| SCHEMBL2471481 | 0.81 | HDAC1 (0.50) | HDAC1HDAC2HDAC3NCOR2MEN1 | |
| SCHEMBL3832438 | 0.75 | HDAC1 (0.41) | HDAC1MEN1ALDH1A1KMT2A | |
| SCHEMBL3835098 | 0.75 | HDAC1 (0.41) | HDAC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2471256 | 0.74 | UTS2R (0.58) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL2480482 | 0.73 | UTS2R (0.55) | HDAC1HDAC2HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | claimed |