Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476211 | 0.91 | HDAC1 (0.56) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2476443 | 0.88 | HDAC1 (0.56) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL2473404 | 0.88 | HDAC1 (0.44) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL3832438 | 0.87 | HDAC1 (0.41) | HDAC1 | |
| SCHEMBL2475971 | 0.86 | HDAC1 (0.54) | HDAC1HDAC3HDAC2EPHA2HDAC4 | |
| SCHEMBL2480482 | 0.85 | UTS2R (0.55) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3834514 | 0.85 | HDAC1 (0.51) | HDAC1HDAC3HDAC2NCOR2EPHA2 | |
| SCHEMBL2478981 | 0.85 | NPC1 (0.42) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2471332 | 0.84 | HDAC1 (0.50) | HDAC1HDAC3HDAC2NCOR2EPHA2 | |
| SCHEMBL3834328 | 0.84 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NCOR2EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |