Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24791130 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2EPHX1EPHX2HSD11B1 | |
| SCHEMBL26893467 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2EPHX1EPHX2HSD11B1 | |
| SCHEMBL24997017 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2EPHX1EPHX2HSD11B1TSHR | |
| SCHEMBL24734642 | 0.79 | — | — | |
| SCHEMBL25784991 | 0.79 | — | — | |
| SCHEMBL21563162 | 0.76 | SMN1; SMN2 (0.37) | SMN1; SMN2EPHX1EPHX2HSD11B1TSHR | |
| SCHEMBL5151714 | 0.73 | ACHE (0.53) | TSHR | |
| SCHEMBL16659920 | 0.73 | ACHE (0.53) | TSHR | |
| SCHEMBL24734693 | 0.72 | ALDH1A1 (0.34) | SMN1; SMN2 | |
| SCHEMBL15314555 | 0.72 | ALDH1A1 (0.34) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256459-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2022-12-08 | — | — | WO | disclosed |