Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.44 |
| ▸ | TET3 | O43151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.44 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.44 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13182920 | 1.00 | CHRM5 (0.53) | CHRM5CHRM3EPHX2NAMPTHTT | |
| SCHEMBL12194678 | 0.90 | CHRM5 (0.52) | CHRM5CHRM3EPHX2NAMPTHTT | |
| SCHEMBL14327401 | 0.89 | KMT2A (0.46) | CHRM5CHRM3EPHX2NAMPTOPRL1 | |
| SCHEMBL2467179 | 0.88 | ALDH1A1 (0.58) | CHRM5CHRM3ALDH1A1OPRL1TET3 | |
| SCHEMBL2467182 | 0.88 | ALDH1A1 (0.58) | CHRM5CHRM3ALDH1A1OPRL1TET3 | |
| SCHEMBL2473441 | 0.87 | CHRM5 (0.48) | CHRM5CHRM3HTTSMN1; SMN2OPRL1 | |
| SCHEMBL10253720 | 0.87 | CHRM5 (0.48) | CHRM5CHRM3HTTSMN1; SMN2OPRL1 | |
| SCHEMBL13593903 | 0.87 | CHRM5 (0.73) | CHRM5CHRM3ALDH1A1TET3KMT2A | |
| SCHEMBL2471608 | 0.87 | CHRM5 (0.73) | CHRM5CHRM3ALDH1A1TET3KMT2A | |
| SCHEMBL13594297 | 0.83 | CHRM3 (0.53) | CHRM5CHRM3EPHX2NAMPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371366-A1 | Heterocyclo inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2011-10-05 | — | — | EP | disclosed |