Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735686 | 0.88 | RXFP1 (0.38) | RXFP1NR4A2CNR2MEN1NPC1 | |
| SCHEMBL20905336 | 0.84 | P2RX7 (0.42) | RXFP1CNR2MEN1KMT2ABRD9 | |
| SCHEMBL24735684 | 0.80 | PIK3CD (0.39) | RXFP1CNR2GPR139BRD9METAP1 | |
| SCHEMBL31167247 | 0.76 | RXFP1 (0.54) | RXFP1CNR2MEN1NPC1RAB9A | |
| SCHEMBL29992092 | 0.75 | RXFP1 (0.59) | RXFP1CNR2MEN1NPC1RAB9A | |
| SCHEMBL15368377 | 0.75 | RXFP1 (0.59) | RXFP1CNR2MEN1NPC1RAB9A | |
| SCHEMBL18254251 | 0.75 | NR4A2 (0.49) | NR4A2CNR2MEN1NPC1RAB9A | |
| SCHEMBL29324602 | 0.74 | RXFP1 (0.52) | RXFP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25752496 | 0.72 | CNR2 (0.38) | RXFP1CNR2NPC1RAB9A | |
| SCHEMBL20905335 | 0.72 | CNR2 (0.44) | RXFP1CNR2BRD9BRD4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022258057-A1 | COMPOUNDS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2022-12-15 | — | — | WO | disclosed |