Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473584 | 0.76 | HTR2C (0.33) | KDM5AKDM4CKDM5B | |
| SCHEMBL2473104 | 0.73 | POLB (0.33) | ALDH1A1MAPK1KDM5AKDM4CKDM5B | |
| SCHEMBL2475422 | 0.66 | HTR2A (0.33) | KDM5AKDM4CKDM5B | |
| SCHEMBL2479420 | 0.65 | CASP6 (0.40) | — | |
| SCHEMBL5437601 | 0.61 | SMN1; SMN2 (0.39) | ALDH1A1MAPK1KDM5AKDM4CKDM5B | |
| SCHEMBL5437592 | 0.61 | SMN1; SMN2 (0.39) | ALDH1A1MAPK1KDM5AKDM4CKDM5B | |
| SCHEMBL30482021 | 0.55 | SMN1; SMN2 (0.39) | ALDH1A1MAPK1KDM5AKDM4CKDM5B | |
| SCHEMBL2625769 | 0.55 | IDO1 (0.42) | ALDH1A1 | |
| SCHEMBL30303044 | 0.55 | MAPK14 (0.40) | KDM5AKDM4CKDM5B | |
| SCHEMBL2476555 | 0.55 | MAPK14 (0.40) | KDM5AKDM4CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787991-B1 | PYRROLO[2,3-c]PYRIDINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE | TAKEDA PHARMACEUTICAL (JP) | 2011-10-05 | — | — | EP | disclosed |