Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | SNCA | P37840 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ARNT | P27540 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5437601 | 0.83 | SMN1; SMN2 (0.39) | POLBATMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5437592 | 0.83 | SMN1; SMN2 (0.39) | POLBATMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2473102 | 0.75 | CCNT1 (0.35) | POLBATMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2473585 | 0.73 | ALDH1A1 (0.31) | ALDH1A1KDM4CKDM5AKDM5BMAPK1 | |
| SCHEMBL5439596 | 0.69 | FBP1 (0.33) | ALDH1A1MAPTKDM4CKDM5AKDM5B | |
| SCHEMBL5439602 | 0.69 | FBP1 (0.33) | ALDH1A1MAPTKDM4CKDM5AKDM5B | |
| SCHEMBL5439591 | 0.69 | FBP1 (0.33) | ALDH1A1MAPTKDM4CKDM5AKDM5B | |
| Potassium Ion SCHEMBL2477023 | 0.67 | FBP1 (0.33) | MAPT | |
| SCHEMBL31053997 | 0.63 | IDO1 (0.45) | MEN1KMT2A | |
| SCHEMBL5572107 | 0.62 | NR3C2 (0.36) | LMNAALDH1A1MAPTKDM4CKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787991-B1 | PYRROLO[2,3-c]PYRIDINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE | TAKEDA PHARMACEUTICAL (JP) | 2011-10-05 | — | — | EP | disclosed |