Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | GJB2 | P29033 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17106818 | 0.82 | HTR1A (0.43) | HSPA5CA1CA2CA9PDE2A | |
| SCHEMBL17106820 | 0.82 | HTR1A (0.43) | HSPA5CA1CA2CA9PDE2A | |
| SCHEMBL25598746 | 0.82 | HTR1A (0.43) | HSPA5CA1CA2CA9PDE2A | |
| SCHEMBL23584717 | 0.81 | HRH4 (0.47) | HSPA5DOT1LTAAR1 | |
| SCHEMBL20144183 | 0.81 | HRH4 (0.47) | HSPA5DOT1LTAAR1 | |
| SCHEMBL10112577 | 0.80 | DOT1L (0.36) | DOT1LGJB2 | |
| SCHEMBL19227796 | 0.79 | PDE2A (0.49) | HSPA5CA1CA2CA9PDE2A | |
| SCHEMBL18636426 | 0.79 | PDE2A (0.49) | HSPA5CA1CA2CA9PDE2A | |
| SCHEMBL22434801 | 0.79 | PDE2A (0.39) | HSPA5CA1CA2CA9PDE2A | |
| SCHEMBL18666890 | 0.79 | HSPA5 (0.36) | HSPA5PDE2ADOT1LTAAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221514-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | GILEAD SCIENCES, INC. (US) | 2022-10-20 | — | — | WO | disclosed |