SCHEMBL247375

SCHEMBL247375

O=C(Oc1cccc(C2CCCCC2)c1C1CCCCC1)Oc1cccc(C2CCCCC2)c1C1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 11/20 0.50
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PTGDR Q13258 5/20 0.40
ABCB1 P08183 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
KMO O15229 1/20 0.37
MMP1 P03956 1/20 0.37
MMP9 P14780 1/20 0.37
MMP12 P39900 1/20 0.37
PTGER2 P43116 1/20 0.37
ACHE P22303 1/20 0.35
CEL P19835 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247376 0.89 PTGDR2 (0.52) PTGDR2MEN1KMT2APTGDRABCB1
SCHEMBL789204 0.85 PTGDR2 (0.62) PTGDR2MEN1KMT2APTGDRPTGER2
SCHEMBL5839212 0.84 PTGDR2 (0.45) PTGDR2MEN1KMT2APTGDRABCB1
SCHEMBL5838999 0.84 PTGDR2 (0.45) PTGDR2MEN1KMT2APTGDRABCB1
SCHEMBL3679820 0.81 PTGDR2 (0.46) PTGDR2MEN1KMT2APTGDRABCB1
SCHEMBL9251165 0.81 PTGDR2 (0.45) PTGDR2MEN1KMT2APTGDRESR1
SCHEMBL1156529 0.79 PTGDR2 (0.52) PTGDR2MEN1KMT2APTGDRACHE
SCHEMBL248210 0.78 PTGDR2 (0.58) PTGDR2MEN1KMT2APTGDR
SCHEMBL28728708 0.78 PTGDR2 (0.43) PTGDR2MEN1KMT2APTGDRABCB1
SCHEMBL28204910 0.78 ABCB1 (0.60) PTGDR2MEN1KMT2AABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
US-9676716-B2 Polycarbonate having improved thermal and mechanical properties and reduced coefficients of thermal expansion COVESTRO DEUTSCHLAND AG (DE) 2017-06-13 US disclosed
US-20150232644-A1 PRODUCTS WITH IMPROVED NON-FLAMMABILITY COVESTRO DEUTSCHLAND AG (DE) 2015-08-20 US disclosed
US-8969477-B2 Polycarbonate compositions having improved mechanical properties BAYER MATERIALSCIENCE AG (DE) 2015-03-03 US disclosed
US-8507635-B2 Modified polycarbonates having improved surface properties BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-08-13 US disclosed
US-8470934-B2 Polycarbonate compositions having improved surface hardness BAYER MATERIALSCIENCE AG (DE) 2013-06-25 US disclosed
US-8329852-B2 Copolycarbonates having improved surface hardness BAYER MATERIALSCIENCE AG (DE) 2012-12-11 US disclosed
US-20120259055-A1 POLYCARBONATE COMPOSITIONS HAVING IMPROVED MECHANICAL PROPERTIES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-10-11 US disclosed
US-20120244359-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-27 US disclosed
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US disclosed
US-20040030090-A1 Polycarbonates, polyester carbonates and polyesters with special branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2004-02-12 US disclosed
US-6646099-B2 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-11-11 US disclosed
US-20030204042-A1 Production and use of high molecular weight aliphatic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-10-30 US disclosed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
US-20030055201-A1 Process for optimising the production of polycarbonate by melt transesterification BAYER AKTIENGESELLSCHAFT (DE) 2003-03-20 US disclosed
US-20030027971-A1 Preparation of copolycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed