SCHEMBL1156529

SCHEMBL1156529

O=C(Oc1ccccc1-c1ccccc1C1CCCCC1)Oc1ccccc1-c1ccccc1C1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 4/20 0.52
PTGS2 P35354 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
NAAA Q02083 1/20 0.39
TSHR P16473 1/20 0.37
EPHX1 P07099 1/20 0.37
POLB P06746 1/20 0.37
PTPN5 P54829 2/20 0.36
PTPN2 P17706 1/20 0.36
PTPRC P08575 1/20 0.36
PTPRF P10586 1/20 0.36
PTPN1 P18031 1/20 0.36
CDC25B P30305 1/20 0.36
PTGDR Q13258 1/20 0.36
HTR1D P28221 1/20 0.36
HTR1B P28222 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1156531 0.89 PTGDR2 (0.55) PTGDR2PTGS2MEN1KMT2ABCHE
SCHEMBL789204 0.87 PTGDR2 (0.62) PTGDR2MEN1KMT2ANAAAEPHX1
SCHEMBL233918 0.80 S1PR1 (0.47) PTGDR2PTGS2MEN1KMT2AEPHX1
SCHEMBL248210 0.80 PTGDR2 (0.58) PTGDR2MEN1KMT2APOLBPTGDR
SCHEMBL247375 0.79 PTGDR2 (0.50) PTGDR2MEN1KMT2AACHEPTGDR
SCHEMBL4476575 0.79 PTGS2 (0.56) PTGDR2PTGS2BCHEACHEPTPN5
SCHEMBL1788879 0.78 PTGDR2 (0.56) PTGDR2MEN1KMT2APTGDRHTR1D
SCHEMBL6575472 0.77 ALDH1A1 (0.51) PTGDR2MEN1KMT2ATSHRPOLB
Phosphine SCHEMBL2085257 0.77 PTGS2 (0.54) PTGDR2PTGS2BCHEACHENAAA
SCHEMBL789205 0.76 PTGDR2 (0.65) PTGDR2MEN1KMT2APTGDRHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
CN-109153776-B Copolycarbonate as support material in 3D printing 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-107207845-B Copolycarbonate compositions comprising PE-waxes with improved processability 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-107207846-B Copolycarbonate compositions comprising diglyceride with improved rheological and optical properties 科思创德国股份有限公司 2020-05-19 CN disclosed
US-20120231278-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-13 US disclosed
US-8044122-B2 Polycarbonate composition containing UV absorber BAYER MATERIALSCIENCE AG (DE) 2011-10-25 US disclosed
US-7879967-B2 End groups containing alkylsiloxane substituted phenol compounds ; extrusion; molding materials BAYER MATERIALSCIENCE AG (DE) 2011-02-01 US disclosed
US-20090258978-A1 POLYCARBONATE COMPOSITION CONTAINING UV ABSORBER BAYER MATERIALSCIENCE AG (DE) 2009-10-15 US disclosed
US-20090137709-A1 POLYOL-CONTAINING, FLAME-RESISTANT POLYCARBONATES, PROCESSES FOR PREPARING THE SAME AND PRODUCTS CONTAINING THE SAME BAYER MATERIALSCIENCE AG (DE) 2009-05-28 US disclosed
US-20080249234-A1 Modified Polycarbonates, Polyester Carbonates and Polyesters Having Improved Elongation Behaviour and Flame Resistance BAYER MATERIALSCIENCE AG (DE) 2008-10-09 US disclosed
US-6767986-B2 A LOW MOLECULAR WEIGHT ALIPHATIC POLYCARBONATE IS PREPARED AND A SECOND STAGE WHERE THE LOW MOLECULAR WEIGHT ALIPHATIC POLYCARBONATE IS CONDENSED WITH DIARYL CARBONATE IN A MELT TRANSESTERIFICATION PROCESS BAYER AKTIENGESELLSCHAFT (DE) 2004-07-27 US disclosed
US-20040143088-A1 Method for producing polycarbonates COVESTRO DEUTSCHLAND AG (DE) 2004-07-22 US disclosed
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US disclosed
US-20040030090-A1 Polycarbonates, polyester carbonates and polyesters with special branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2004-02-12 US disclosed
US-6646099-B2 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-11-11 US disclosed
US-20030204042-A1 Production and use of high molecular weight aliphatic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-10-30 US disclosed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed