Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165679 | 0.84 | NPSR1 (1.00) | NPSR1KMT2AMEN1KDM4E | |
| SCHEMBL15340931 | 0.83 | MEN1 (0.49) | NPSR1SIGMAR1CHRM3CHRM5HSD17B10 | |
| SCHEMBL15271453 | 0.81 | NPSR1 (0.47) | NPSR1SIGMAR1CHRM3CHRM5HSD17B10 | |
| SCHEMBL718206 | 0.80 | NPSR1 (0.82) | NPSR1CHRM3CHRM5CA2CA12 | |
| SCHEMBL1021302 | 0.80 | MEN1 (0.59) | NPSR1SIGMAR1CHRM3CHRM5HSD17B10 | |
| SCHEMBL18628083 | 0.80 | SIGMAR1 (0.47) | NPSR1SIGMAR1CHRM3CHRM5HSD17B10 | |
| SCHEMBL11830885 | 0.79 | HSD17B10 (0.44) | NPSR1SIGMAR1CHRM3CHRM5HSD17B10 | |
| Hydrochloric Acid SCHEMBL1546550 | 0.79 | MEN1 (0.58) | NPSR1SIGMAR1CHRM3CHRM5HSD17B10 | |
| Hydrochloric Acid SCHEMBL2014381 | 0.79 | MEN1 (0.58) | NPSR1SIGMAR1CHRM3CHRM5HSD17B10 | |
| SCHEMBL5423698 | 0.78 | NPSR1 (0.78) | NPSR1KMT2AMEN1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253283-A1 | PROTEIN KINASE DEGRADANT AND USE THEREOF | 中国科学院上海有机化学研究所 | 2022-12-08 | — | — | WO | disclosed |