Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718206 | 0.98 | NPSR1 (0.82) | NPSR1ALDH1A1NPC1KDM4EHTT | |
| Acetic Acid SCHEMBL27274362 | 0.96 | NPSR1 (0.72) | NPSR1ALDH1A1NPC1KDM4EHTT | |
| SCHEMBL13165679 | 0.88 | NPSR1 (1.00) | NPSR1ALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL11421204 | 0.81 | ALDH1A1 (0.50) | NPSR1ALDH1A1NPC1TDP1MAPT | |
| SCHEMBL13993828 | 0.80 | NPSR1 (0.83) | NPSR1ALDH1A1KDM4ETDP1CA12 | |
| SCHEMBL7105166 | 0.79 | NPSR1 (0.50) | NPSR1ALDH1A1NPC1KDM4EHTT | |
| SCHEMBL24737682 | 0.78 | NPSR1 (0.72) | NPSR1KDM4ECA12CA1CA2 | |
| SCHEMBL84855 | 0.78 | NPC1 (0.64) | NPSR1ALDH1A1NPC1KDM4EMAPT | |
| SCHEMBL14385466 | 0.78 | NPSR1 (0.72) | NPSR1ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL8139355 | 0.78 | NPC1 (0.64) | NPSR1ALDH1A1NPC1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
| US-20220315556-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-10-06 | — | — | US | disclosed |
| US-20140147386-A1 | 1-ARYL-4-METHYL-[1,2,4]TRIAZOLO[4,3-a]QUINOXALINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2014-05-29 | — | — | US | disclosed |
| US-20070111981-A1 | New (hetero)aryl compounds with MCH antagonistic activity and medicaments comprising these compounds | ROTH GERALD J | 2007-05-17 | — | — | US | disclosed |
| EP-0342675-A2 | Novel quinolonecarboxylic acid derivatives | Chugai Seiyaku Kabushiki Kaisha (JP) | 1989-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070111981-A1 | New (hetero)aryl compounds with MCH antagonistic activity and medicaments comprising these compounds | MCHR1, GPR119, MCHR2 | NPSR1 76/4885ALDH1A1 3960/4885NPC1 1939/4885 |
| US-20220315556-A1 | FURIN INHIBITORS | FURIN, TGFB1, PCSK7 | NPSR1 2459/4885ALDH1A1 3733/4885NPC1 250/4885 |
| US-20140147386-A1 | 1-ARYL-4-METHYL-[1,2,4]TRIAZOLO[4,3-a]QUINOXALINE DERIVATIVES | PDE2A, PDE12, PDE5A | NPSR1 1740/4885ALDH1A1 929/4885NPC1 2810/4885 |
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | NPSR1 2459/4885ALDH1A1 3733/4885NPC1 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.