Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 8/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 8/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24739447 | 0.92 | SRC (0.36) | MCL1SRCGPR119P2RX3 | |
| SCHEMBL24739230 | 0.92 | P2RX3 (0.44) | MCL1CYP1A2CYP3A4SRCP2RX3 | |
| SCHEMBL24739530 | 0.92 | SRC (0.42) | MCL1SRC | |
| SCHEMBL24740460 | 0.88 | GPR119 (0.41) | MCL1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL24739050 | 0.88 | GPR119 (0.41) | MCL1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL24739541 | 0.86 | HRH3 (0.37) | CYP1A2POLBCYP3A4CYP2C19SRC | |
| SCHEMBL24739114 | 0.85 | TP53 (0.38) | POLBSRCP2RX3 | |
| SCHEMBL24739538 | 0.85 | TP53 (0.38) | POLBSRCP2RX3 | |
| SCHEMBL24739168 | 0.82 | SRC (0.36) | CYP1A2POLBCYP3A4CYP2C19SRC | |
| SCHEMBL24739552 | 0.82 | SRC (0.39) | SRCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | disclosed |