Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.69 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.69 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.69 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.69 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 6/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | GJB2 | P29033 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22927975 | 1.00 | SSTR1 (0.69) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL24378405 | 1.00 | SSTR1 (0.69) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL6298172 | 0.97 | SSTR1 (0.72) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL7541760 | 0.97 | SSTR1 (0.72) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL7148930 | 0.97 | SSTR1 (0.72) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL11446298 | 0.97 | SSTR1 (0.72) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL24122546 | 0.97 | SSTR1 (0.72) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL23343941 | 0.97 | SSTR1 (0.72) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL14021065 | 0.97 | SSTR1 (0.72) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL3065395 | 0.97 | SSTR1 (0.72) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524026-B2 | Heparanase inhibitors for treatment of diabetes | WAYNE STATE UNIVERSITY (US) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524026-B2 | Heparanase inhibitors for treatment of diabetes | HPSE, ENGASE, HEXD | SSTR1 691/4885SSTR2 848/4885SSTR4 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.