SCHEMBL7148930

SCHEMBL7148930

CO[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SSTR1 P30872 1/20 0.72
SSTR2 P30874 1/20 0.72
SSTR4 P31391 1/20 0.72
SSTR3 P32745 1/20 0.72
SSTR5 P35346 1/20 0.72
BCHE P06276 1/20 0.56
PTPN1 P18031 10/20 0.55
PTPN2 P17706 5/20 0.55
NT5E P21589 1/20 0.54
GJB2 P29033 1/20 0.53
CDC25B P30305 6/20 0.53
PTPN11 Q06124 3/20 0.51
PTPN6 P29350 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7155707 1.00 SSTR1 (0.72) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL7541760 1.00 SSTR1 (0.72) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL14021065 1.00 SSTR1 (0.72) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL7545074 1.00 SSTR1 (0.72) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL23343941 1.00 SSTR1 (0.72) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL11446298 1.00 SSTR1 (0.72) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL24122546 1.00 SSTR1 (0.72) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL6298172 1.00 SSTR1 (0.72) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL3065395 1.00 SSTR1 (0.72) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL19400314 1.00 SSTR1 (0.72) SSTR1SSTR2SSTR4SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2822653-B1 NEW C-GLYCOSYLPOLYPHENOL ANTIDIABETIC AGENTS, EFFECT ON GLUCOSE TOLERANCE AND INTERACTION WITH BETA-AMYLOID. THERAPEUTIC APPLICATIONS OF THE SYNTHESIZED AGENT(S) AND OF GENISTA TENERA ETHYL ACETATE EXTRACTS CONTAINING SOME OF THOSE AGENTS FACULDADE DE CIENCIAS DA UNIV DE LISBOA (PT) 2024-06-19 EP disclosed
EP-3052134-B1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES MERCK SHARP & DOHME (US) 2021-05-05 EP disclosed
CN-105792852-B Glucose-responsive insulin conjugates 默沙东公司 2019-12-10 CN disclosed
US-20180110863-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES MERCK SHARP & DOHME CORP. (US) 2018-04-26 US disclosed
CN-105153251-B A kind of Benzylation method of monose first glycosides 浙江合糖科技有限公司 2018-03-20 CN disclosed
EP-3280450-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES Merck Sharp & Dohme Corp. (US) 2018-02-14 EP disclosed
US-9889205-B2 Glucose-responsive insulin conjugates MERCK SHARP & DOHME CORP. (US) 2018-02-13 US disclosed
US-9884125-B2 Glucose-responsive insulin conjugates MERCK SHARP & DOHME CORP. (US) 2018-02-06 US disclosed
US-20170348340-A1 NEW C-GLYCOSYLPOLYPHENOL ANTIDIABETIC AGENTS, EFFECT ON GLUCOSE TOLERANCE AND INTERACTION WITH BETA-AMYLOID. THERAPEUTIC APPLICATIONS OF THE SYNTHESIZED AGENT(S) AND OF GENISTA TENERA ETHYL ACETATE EXTRACTS CONTAINING SOME OF THOSE AGENTS UNIVERSIDADE DE LISBOA (50%) (PT) 2017-12-07 US disclosed
US-9775856-B2 C-glycosylpolyphenol antidiabetic agents, effect on glucose tolerance and interaction with beta-amyloid. therapeutic applications of the synthesized agent(s) and of Genista tenera ethyl acetate extracts containing some of those agents FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) 2017-10-03 US disclosed
US-5627270-A Glycosylated steroid derivatives for transport across biological membranes and process for making and using same TRUSTEES OF PRINCETON UNIVERSITY (US) 1997-05-06 US disclosed
US-5622936-A COMPLEX OF SUGAR WITH A PHOSPHORUS AMIDE DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) 1997-04-22 US disclosed
EP-0729648-A4 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LTD (AU) 1997-01-02 EP disclosed
WO-1996035239-A1 HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1996-11-07 WO disclosed
EP-0729648-A1 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1996-09-04 EP disclosed
WO-1995012219-A1 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1995-05-04 WO disclosed
EP-0369182-B1 Antitumour saccharide conjugates DEUTSCHES KREBSFORSCH (DE) 1995-03-29 EP disclosed
EP-0369182-A1 Antitumour saccharide conjugates Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 1990-05-23 EP disclosed
WO-1990004597-A1 TUMOR-INHIBITING SACCHARIDE CONJUGATES Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 1990-05-03 WO disclosed
US-4207413-A ARTIFICIAL SWEETENER QUEEN'S UNIVERSITY AT KINGSTON (CA) 1980-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180110863-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES GPR119, INSR, IRS1 SSTR1 70/4885SSTR2 120/4885SSTR4 51/4885
US-20170348340-A1 NEW C-GLYCOSYLPOLYPHENOL ANTIDIABETIC AGENTS, EFFECT ON GLUCOSE TOLERANCE AND INTERACTION WITH BETA-AMYLOID. THERAPEUTIC APPLICATIONS OF THE SYNTHESIZED AGENT(S) AND OF GENISTA TENERA ETHYL ACETATE EXTRACTS CONTAINING SOME OF THOSE AGENTS IAPP, GBA3, GANAB SSTR1 3162/4885SSTR2 3805/4885SSTR4 2130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.